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Alternating hemiplegia of childhood: clinical manifestations and long-term outcome. It may become difficult to find a comfortable position for arms and legs with even the minor exertions associated with holding arms crossed causing significant pain similar to restless leg syndrome. Jon; Allanson, Judith E. Analysis of ATP1A3 revealed the heterozygous substitution c. Guidelines for which disorders to consider and what tests to employ vary among different centers. An international study in 12 children. Primary dystonia is suspected when the dystonia is the only sign and there is no identifiable cause or structural abnormality in the central nervous system.
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