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Reducing sodium intake does lead to a slightly lower average blood pressure. However, over the next 16 years, the researchers found that the study participants who consumed less than 2, milligrams of sodium a day had higher blood pressure than participants who consumed higher amounts of sodium. Treatment of borderline hypertension–moderate salt restriction in the treatment of borderline hypertension. Make an appointment. The effect of sodium depletion and potassium supplementation on vasopressin, renin and catecholamines in hypertensive men. Sodium and potassium fluxes and concentrations in erythrocytes of normal subjects during prolonged sodium depletion and repletion. Part 1, Prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias.